How does it work?

 Xenical capsules contain the active ingredient orlistat, which is a type of medicine called a lipase inhibitor. It is used to aid weight loss in people who are obese.

Orlistat is not absorbed into the bloodstream, but works locally in the stomach and small intestine, where it prevents the action of two compounds found in the digestive juices. These compounds (known as enzymes) are called gastric and pancreatic lipases. They normally break down fats that we consume in our diet.

The fats we consume in our diets are made of molecules that are too large to be absorbed from the gut into the bloodstream. They need to be broken down into smaller molecules during the process of digestion, in order to be absorbed into the bloodstream. Gastric and pancreatic lipases are the compounds in the gut that carry out this function.

Orlistat works by preventing gastric and pancreatic lipases from working. It is taken at mealtimes to prevent fat that is eaten in the meals from being broken down and absorbed by the body. This means the body cannot use the fat as a source of energy, or convert it into fat tissue. Instead, the fat is excreted in the faeces. This helps weight loss.

What are some possible side effects of Xenical? (This is NOT a complete list of side effects reported with Xenical. Your health care provider can discuss with you a more complete list of side effects.)

  • Oily spotting
  • Gas with discharge
  • Urgent need to have a bowel movement
  • Oily or fatty stools
  • Oily discharge
  • Increased number of bowel movements
  • Inability to control bowel movements

For more detailed information about Xenical, ask your health care provider.